Microwave Magnetic Properties and Natural Resonance of e-Co Nanoparticles

Owing to the novel crystal structure, ε-Co nanoparticles with an average diameter of 12 nm are synthesized and the microwave magnetic properties of the epoxy resin composite with 50voi% ε-Co particles are measured in the frequency range 0.1-7 GHz. The experimental resonance frequency （4.7 GHz） matches well with the values obtained by the theoretical calculation with the Kittel equation and fitting the experimental permeability dispersion curve via the Landan-Lifshitz equation. Hence the resonance peak is attributed to natural resonance mode. This work is believed to be beneficial for further understanding microwave applications of the novel ε-Co nanoparticles.     

Photoinitiated RAFT polymerization of vinyl acetate

A photoinitiation process was investigated to develop a rapid and well‐controlled RAFT polymerization method applied to vinyl acetate (VAc) using methyl (ethoxycarbonothioyl)sulfanyl acetate (MESA) and bis(2,4,6‐trimethylbenzoyl)phenylphosphine oxide as the RAFT agent and photoinitiator, respectively. MESA was selected as the photochemically inert RAFT agent to minimize photolysis of the thiocarbonylthio groups during polymerization. Poly(vinyl acetate) with a prespecified well‐controlled molecular weight (MW) and a narrow MW distribution was successfully synthesized. The polymerization reaction proceeded as a living polymerization and was remarkably rapid compared with approaches that use thermally initiated processes with a very short induction period. A detailed kinetic study of the mechanism underlying the polymerization reaction, however, revealed that the chain ends containing xanthate moieties were not perfectly stable upon UV‐irradiation, and they generated radicals via homolytic cleavage. This reaction appeared to proceed by a combination of a degenerative transfer RAFT mechanism and a dissociation‐combination mechanism. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012     

Design,synthesis and in vivo anti-hyperglycemic activity of gem-dimethyl-bearing C-glucosides as SGLT2 inhibitors

A series of gem-dimethyl-bearing C-glucosides were designed and synthesized as SGLT2 inhibitors,with anhydrous aluminum chloride-mediated Friedel-Crafts alkylation to construct the gem-dimethyl functionality being the key step.The in vivo anti-hyperglycemic activity was evaluated with mice oral glucose tolerance test(OGTT),and all the synthesized compounds showed significant but less potent anti-hyperglycemic activity than the positive control dapagliflozin.     

Stochastic Resonance in a Time-Delayed Mono-Stable System with Multiplicative and Additive Noise

The stochastic resonance （SR） in a time-delayed mono-stable system driven by multiplicative white noise, additive white noise, additive dichotomous noise as well as a periodic square-wave signal is considered from the view of the signal-to-noise ratio （SNR）. It is found that the SNR increases monotonically with the increase of the delay time. The SNR exhibits the SR behavior when it is plotted as a function of intensities of the noises, displaying the asymmetry of the dichotomous noise. The SNR varies non-monotonically with the increase of the system parameter and the amplitude of the input square-wave signal.     

矩形毛细微槽中三角形区域接触线特性的研究

利用CCD和宽视场体视显微镜相结合的技术,拍摄了矩形毛细微槽内液体工质在三角形区域的润湿图像,并进行了图像处理,研究结果表明:随着热流密度的增加,三角形区域内的三相接触线向微槽底角收缩,导致三相接触线的长度减小,液膜厚度减小;随着微槽深度的增加,三角形区域的接触线长度减小;随着微槽宽度和倾斜角度的增加,三角形区域内的接触线长度增加,液膜厚度增加.     

Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening

Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions. Dibenzocyclooctyne derivatives (DIBAC and BARAC) were identified to be especially reactive dipolarophiles, which undergo the (3 + 2) cycloadditions with N-phenyl sydnone with the rate constant of up to 1.46 M^–1 s^–1. Most significantly, the sydnone-dibenzocyclooctyne and norbornene-tetrazine cycloadditions were predicted to be mutually orthogonal. This was validated experimentally and used for highly selective fluorescence labeling of two proteins simultaneously.